Bipolar disorders: differential diagnosis

Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .

Bipolar disorders: differential diagnosis. Major unipolar depression, Schizoaffective disorder, Schizophrenia. Fully referenced neurology checklist.

Psychiatric differentials of mania

  • Major unipolar depression
  • Schizoaffective disorder
  • Schizophrenia
  • Anxiety disorders
  • Personality disorders: borderline or antisocial
  • Attention deficit hyperactivity disorder (ADHD)

Medical differentials of mania

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Drug differentials of mania

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Medical differential of depression

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Neurological differentials of depression

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Drug differentials of depression

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References

  1. Hilty DM, Leamon MH, Lim RF, Kelly RH, Hales RE. A review of bipolar disorder in adults. Psychiatry (Edgmont) 2006; 3:43-55.
  2. McIntyre RS, Calabrese JR. Bipolar depression: the clinical characteristics and unmet needs of a complex disorder. Curr Med Res Opin 2019; 35:1993-2005.
  3. Connolly KR, Thase ME. The clinical management of bipolar disorder: a review of evidence-based guidelines. Prim Care Companion CNS Disord 2011; 13:PCC.10r01097.
  4. Price AL, Marzani-Nissen GR. Bipolar disorders: a review. Am Fam Physician 2012; 85:483-493.

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