Behcet’s syndrome: treatment

Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .

Behcet’s syndrome: treatment. Methylprednisolone 1g IV daily for 3-10 days. Fully referenced neurology checklist.

Steroid therapy

  • Methylprednisolone 1g IV daily for 3-10 days
  • This is followed by oral steroids for about 6 months

Immunosuppression for significant parenchymal relapses

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Second line therapies

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References

  1. Akman-Demir G, Serdaroglu P. Neuro-Behçet’s disease: a practical approach to diagnosis and treatment. Pract Neurol 2002; 2:340-347.
  2. Kalra S, Silman A, Akman-Demir G, et al. Diagnosis and management of Neuro-Behcet’s disease: international consensus recommendations. J Neurol 2014; 261:1662-1676.
  3. Zeydan B, Uygunoglu U, Saip S, et al. Infliximab is a plausible alternative for neurologic complications of Behçet disease. Neurol Neuroimmunol Neuroinflamm 2016; 3:e258. 
  4. Kidd DP. Rituximab is effective in severe treatment-resistant Behcet’s syndrome. J Neurol 2015; 262:2676-2677.

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