Basal ganglia calcification

Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .

Basal ganglia calcification. Tuberous sclerosis (TS), Neurofibromatosis (NF), Cerebral haemorrhage. Fully referenced neurology checklist.

Neurological causes

  • Primary familial basal ganglia calcification (PFBC; Fahr disease)
  • Tuberous sclerosis (TS)
  • Neurofibromatosis (NF)
  • Cerebral haemorrhage
  • Cavernous haemangioma
  • Parkinsonism
  • Nervous system infections
  • Hastings-James syndrome (idiopathic lenticulo-dentate calcification)
  • Leukoencephalopathy, cerebral calcifications, and cysts
  • Nasu Hakola disease

Metabolic disorders

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Toxic causes

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Infective causes

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Endocrine causes

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Connective tissue diseases

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Iatrogenic causes

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References

  1. Harrington MG, Macpherson P, McIntosh WB, Allam BF, Bone I. The significance of incidental finding of basal ganglia calcification on computed tomography. JNNP 1981; 44:1168-1170.
  2. Fenelon G, Gray F, Paillard F, Thibierge M, Mahieux F, Guillard A. A prospective study of patients with CT detected pallidal calcifications. JNNP 1993; 56:622-625.
  3. Hagiwara N, Yahikozawa H. Multiple cavernous haemangioma showing marked calcification on cranial radiography. JNNP 2002; 72:410.
  4. Sprengelmeyer R. The neurology of disgust. Brain 2007; 130:1715-1717.
  5. Klünemann HH, Ridha BH, Magy L, et al. The genetic causes of basal ganglia calcification, dementia, and bone cysts: DAP12 and TREM2. Neurology 2005; 64:1502-1507.
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