Aspergillosis: management

Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .

Aspergillosis: management. Hypointense lesions on T2-weighted imaging. Fully referenced neurology checklist.

Magnetic resonance imaging (MRI) brain: features

  • Hypointense lesions on T2-weighted imaging
  • Contrast enhancement: bright, solid, and homogenous
  • Cavernous extension: if there is associated paranasal disease
  • Target sign: on diffusion weighted imaging (DWI)

Other investigations

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Antifungal treatment

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Alternative antifungal treatments

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Surgery: indications

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References

  1. Nadkarni T, Goel A. Aspergilloma of the brain: an overview. J Postgrad Med. 2005; 51(Suppl 1):S37-S41.
  2. Kumar D, Nepal P, Singh S, et al. CNS aspergilloma mimicking tumors: review of CNS aspergillus infection imaging characteristics in the immunocompetent population. J Neuroradiol 2018; 45:169-176.
  3. Finelli PF. MR target sign in cerebral aspergillosis. Neurohospitalist 2020; 10:287-290.

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