Apomorphine test

Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .

Apomorphine test. The response to Apomorphine may predict Levodopa-responsiveness. Fully referenced neurology checklist.

Usefulness

  • The response to Apomorphine may predict Levodopa-responsiveness
  • It is not indicated for making the diagnosis of Parkinson’s disease (PD)

Pre-procedure Domperidone

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Pre-procedure protocol

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Procedure protocol

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Indicators of a positive test

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Post procedure assessment

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Side effects of Apomorphine

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Acronym

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References

  1. Lees A, Turner K. Apomorphine for Parkinson’s disease. Pract Neurol 2002; 2:280-286.
  2. Association of British Neurologists (ABN) guidelines on Domperidone in Parkinson’s disease. Accessed 23rd of April 2016.
  3. Katzenschlager R. A reappraisal of apomorphine. ACNR 2015; 15:14-16.
  4. D'Costa DF, Abbott RJ, Pye IF, Millac PA. The apomorphine test in parkinsonian syndromes. JNNP 1991; 54:870-872.
  5. Clarke CE, Davies P. Systematic review of acute levodopa and apomorphine challenge tests in the diagnosis of idiopathic Parkinson’s disease. JNNP 2000; 69:590–594.

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