Anticoagulant-induced intracerebral haemorrhage (ICH): risk factors and outcomes

Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .

Anticoagulant-induced intracerebral haemorrhage (ICH): risk factors and outcomes. Hypertension. Fully referenced neurology checklist.

Risk factors

  • Hypertension
  • The risk may be higher with Rivaroxaban than with Dabigatran

Epidemiology

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Outcomes

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References

  1. Majeed A, Kim YK, Roberts RS, Holmstrom M, Schulman S. Optimal timing of resumption of warfarin after intracranial hemorrhage. Stroke 2010; 41:2860-2866.
  2. Toyoda K, Yasaka M, Uchiyima S, et al. Blood pressure levels and bleeding events during antithrombotic therapy: the bleeding with antithrombotic therapy (BAT) study. Stroke 2010; 41:1440-1444.
  3. Graham DJ, Reichman ME, Wernecke M, et al. Stroke, bleeding, and mortality risks in elderly medicare beneficiaries treated with dabigatran or rivaroxaban for nonvalvular atrial fibrillation. JAMA Intern Med 2016; 176:1662-1671.
  4. Wu TY, Yassi N, Shah DG, et al. Simultaneous multiple intracerebral hemorrhages (SMICH). Stroke 2017; 48:581-586. 
  5. Boulouis G, Morotti A, Pasi M, Goldstein JN, Gurol ME, Charidimou A. Outcome of intracerebral haemorrhage related to non-vitamin K antagonists oral anticoagulants versus vitamin K antagonists: a comprehensive systematic review and meta-analysis. JNNP 2017; pii: jnnp-2017-316631 (Epub ahead of print).
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