Anti TNF-α neurological syndromes
Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .
Anti TNF-α neurological syndromes. Adalimumab, Certolizumab, Etanercept, Golimumab, Infliximab. Fully referenced neurology checklist.
TNFα inhibitor drugs
- Adalimumab
- Certolizumab
- Etanercept
- Golimumab
- Infliximab
Central nervous system presentations
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Peripheral nervous system presentations
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Magnetic resonance imaging (MRI) features
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Cerebrospinal fluid (CSF) analysis
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Neurophysiology
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Treatment
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References
- Ali F, Laughlin RS. Asymptomatic CNS demyelination related to TNF-α inhibitor therapy. Neurol Neuroimmunol Neuroinflamm 2016; 4:e298.
- Seror R, Richez C, Sordet C, et al; Club Rhumatismes et Inflammation Section of the SFR. Pattern of demyelination occurring during anti-TNF-α therapy: a French national survey. Rheumatology (Oxford) 2013; 52:868-874.
- Tejera-Segura B, Ferraz-Amaro I. Biological therapy and neurological manifestations. What do we know? Reumatol Clin 2016; pii: S1699-258X(16)30042-0 ([Epub ahead of print).
- Li SY, Birnbaum AD, Goldstein DA. Optic neuritis associated with adalimumab in the treatment of uveitis. Ocul Immunol Inflamm 2010; 18:475-481.
- Fockaert N, Goffin K, Demaerel P, Van Paesschen W. Infliximab-associated autoimmune limbic encephalitis: a case report. Acta Neurol Belg 2015; 115:161-163.
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