Anti-seizure medications (ASMs): dosing summary
Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .
Anti-seizure medications (ASMs): dosing summary. The dose is 4 mg/kg/day. Fully referenced neurology checklist.
Acetazolamide
- The dose is 4 mg/kg/day
- The typical adult dose is 500-1000 mg daily
- The standard formulation is administered in 3-4 divided doses
- The extended-release formulation is administered in 1 to 2 divided doses
Brivaracetam
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Carbamazepine
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Clobazam
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Clonazepam
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Eslicarbazepine
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Ethosuximide
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Felbamate
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Gabapentin
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Lacosamide
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Lamotrigine
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Levetiracetam
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Oxcarbazepine
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Perampanel
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Phenobarbitone
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Phenytoin
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Piracetam
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Pregabalin
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Primidone
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Rufinamide in adults
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Rufinamide in children ≥4 years
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Stiripentol
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Sulthiame
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Tiagabine
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Topiramate
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Valproate
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Vigabatrin
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Zonisamide
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Acronyms
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Acetazolamide
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Brivaracetam
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Carbamazepine
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Clobazam
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Clonazepam
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Eslicarbazepine
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Ethosuximide
Locked: subscribe to see this section.
Felbamate
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Gabapentin
Locked: subscribe to see this section.
Lacosamide
Locked: subscribe to see this section.
Lamotrigine
Locked: subscribe to see this section.
Levetiracetam
Locked: subscribe to see this section.
Oxcarbazepine
Locked: subscribe to see this section.
Perampanel
Locked: subscribe to see this section.
Phenobarbitone
Locked: subscribe to see this section.
Phenytoin
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Piracetam
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Pregabalin
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Primidone
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Rufinamide in adults
Locked: subscribe to see this section.
Rufinamide in children ≥4 years
Locked: subscribe to see this section.
Stiripentol
Locked: subscribe to see this section.
Sulthiame
Locked: subscribe to see this section.
Tiagabine
Locked: subscribe to see this section.
Topiramate
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Valproate
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Vigabatrin
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Zonisamide
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Acronyms
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References
- Reiss WG, Oles KS. Acetazolamide in the treatment of seizures. Ann Pharmacother 1996; 30:514-519.
- Ferlazzo E, Russo E, Mumoli L, et al. Profile of brivaracetam and its potential in the treatment of epilepsy. Neuropsychiatr Dis Treat 2015; 11:2967-2973.
- Goldenberg MM. Overview of drugs used for epilepsy and seizures: etiology, diagnosis, and treatment. P T 2010; 35:392-415.
- Powell G, Saunders M, Marson AG. Immediate-release versus controlled-release carbamazepine in the treatment of epilepsy. Cochrane Database Syst Rev 2014; 2:CD007124.
- Gauthier AC, Mattson RH. Clobazam: a safe, efficacious, and newly rediscovered therapeutic for epilepsy. CNS Neurosci Ther 2015; 21:543-548.
- And 35 more. Subscribe to see the full list
