Anti-MUSK myasthenia gravis (MG): investigations
Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .
Anti-MUSK myasthenia gravis (MG): investigations. This shows facial muscle abnormalities in about 75% of cases. Fully referenced neurology checklist.
Electromyogram (EMG)
- This shows facial muscle abnormalities in about 75% of cases
- Single-fiber EMG is often normal
- The EMG features may mimic inflammatory myopathy
- There may be myotonic discharges
Chest CT
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References
- Wolfe GI, Oh SJ. Clinical phenotype of muscle-specific tyrosine kinase-antibody-positive myasthenia gravis. Ann N Y Acad Sci 2008; 1132:71-75.
- Takahashi H, Kawaguchi N, Ito N, Takamichi H, Kuwabara S. Is tongue atrophy reversible in anti-MUSK myasthenia gravis? Six year observation. JNNP 2010; 81:701-702.
- Sieb JP. Myasthenia gravis: an update for the clinician. Clin Exp Immunol 2014; 175:408-418.
- Skolka M, Lamb CJ, Rubin DI, Klein CJ, Laughlin RS. Electrodiagnostic characteristics suggestive of muscle-specific kinase myasthenia gravis. Neurol Clin Pract 2022; 12:211-217.
- Skolka M, Lamb CJ, Rubin DI, Klein CJ, Laughlin RS. Electrodiagnostic characteristics suggestive of muscle-specific kinase myasthenia gravis. Neurol Clin Pract 2022; 12:211-217.
