Anti DPPX autoimmune encephalitis: management
Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .
Anti DPPX autoimmune encephalitis: management. White cell counts: there is a lymphocytic pleocytosis. Fully referenced neurology checklist.
Cerebrospinal fluid (CSF) analysis
- White cell counts: there is a lymphocytic pleocytosis
- Oligoclonal bands (OCBs): these are present
Electroencephalogram (EEG)
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Magnetic resonance imaging (MRI) brain
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Treatment
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References
- Stokin GB, Popović M, Gelpi E, Kogoj A, Dalmau J, Graus F. Neuropathologic features of anti-dipeptidyl-peptidase-like protein-6 antibody encephalitis. Neurology 2015; 84:430-432.
- Stoeck K, Carstens PO, Jarius S, et al. Prednisolone and azathioprine are effective in DPPX antibody-positive autoimmune encephalitis. Neurol Neuroimmunol Neuroinflamm 2015; 2:e86.
- Heuer C, Disse L, Ledergerber D, Jelcic I, Imbach LL. EEG-Delta brushes in DPPX encephalitis - welcome to the club. Clin Neurophysiol Pract 2022; 8:12-15.
- Balint B, Jarius S, Nagel S, et al. Progressive encephalomyelitis with rigidity and myoclonus: a new variant with DPPX antibodies. Neurology 2014; 82:1521-1528.
