Anti CV2/CRMP5 antibody paraneoplastic syndrome: management
Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .
Anti CV2/CRMP5 antibody paraneoplastic syndrome: management. The Pulvinar sign, Basal ganglia high signal. Fully referenced neurology checklist.
Magnetic resonance imaging (MRI) brain: features
- The Pulvinar sign
- Basal ganglia high signal
- Selective external capsule involvement: case report
Cerebrospinal fluid (CSF) analysis
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Treatment of paraneoplastic chorea
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Acronym
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References
- Wang S, Hou H, Tang Y, et al. An overview on CV2/CRMP5 antibody-associated paraneoplastic neurological syndromes. Neural Regen Res 2023; 18:2357-2364.
- Vernino S, Tuite P, Adler CH, et al. Paraneoplastic chorea associated with CRMP-5 neuronal antibody and lung carcinoma. Ann Neurol 2002; 51:625-630.
- Tada S, Furuta M, Fukada K, et al. Severe parkinsonism associated with anti-CRMP5 antibody-positive paraneoplastic neurological syndrome and abnormal signal intensity in the bilateral basal ganglia. JNNP 2016; 87:907-910.
- Nakajima M, Uchibori A, Ogawa Y, et al. A case of CV2/CRMP5-antibody-related paraneoplastic optic neuropathy associated with small-cell lung cancer. Intern Med 2018; 57:1645-1649.
- Chu L, Clift F. Anti-CV2/CRMP5 antibody-associated hemorrhagic leukoencephalomyelitis treated with steroids, intravenous immunoglobulin, plasmapheresis, and cyclophosphamide. Mult Scler Relat Disord 2020; 40:101964.
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