Anti-basal ganglia antibody (ABGA) syndrome
Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .
Anti-basal ganglia antibody (ABGA) syndrome. Sydenham's chorea, Encephalitis lethargica, PANDAS. Fully referenced neurology checklist.
Causes
- Sydenham's chorea
- Post streptococcal acute demyelinating encephalomyelitis (ADEM)
- Encephalitis lethargica
- PANDAS
- Tourette syndrome (TS)
- Obsessive compulsive disorder (OCD)
- Infantile bilateral pallidal necrosis
- Paroxysmal dystonic choreoathetosis
- Fixed dystonia syndrome
- Anxiety disorders
- Depressive disorders
- Enuresis
- Conduct disorder
- Attention deficit hyperactivity disorder (ADHD)
Clinical features of adult onset ABGA
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Treatment
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References
- Martino D, Church A, Giovannoni G. Are antibasal ganglia antibodies important, and clinical useful? Pract Neurol 2007; 7:32-41.
- Dale RC, Church AJ, Surtees RA, et al. Encephalitis lethargica syndrome : 20 new cases and evidence of basal ganglia autoimmunity. Brain 2004; 127:21-33.
- Edwards MJ, Trikouli E, Martino D, et al. Anti-basal ganglia antibodies in patients with atypical dystonia and tics: a prospective study. Neurology 2004; 63:156-158.
- Edwards MJ, Dale RC, Church AJ, Giovannoni G, Bhatia KP. A dystonic syndrome associated with anti-basal ganglia antibodies. JNNP 2004; 75:914-916.
- Nicholson TR, Ferdinando S, Krishnaiah RB, et al. Prevalence of anti-basal ganglia antibodies in adult obsessive-compulsive disorder: cross-sectional study. Br J Psychiatry 2012; 200:381-386.
