ANCA associated vasculitis (AAV): antibodies

Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .

ANCA associated vasculitis (AAV): antibodies. P-ANCA antibodies are perinuclear staining. Fully referenced neurology checklist.

P-ANCA

  • P-ANCA antibodies are perinuclear staining
  • They are antibodies against myeloperoxidase (MPO)
  • They are present mainly in MPA, EGPA and renal-limited vasculitis
  • They may also occur in GPA

C-ANCA

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X-ANCA

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Acronym

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References

  1. Chung SA, Seo P. Microscopic polyangiitis. Rheum Dis Clin North Am 2010; 36:545-558.
  2. Arman F, Barsoum M, Selamet U, et al. Antineutrophil cytoplasmic antibody-associated vasculitis, update on molecular pathogenesis, diagnosis, and treatment. Int J Nephrol Renovasc Dis 2018; 11:313-319.

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