Acute necrotizing encephalopathy (ANE1): management
Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .
Acute necrotizing encephalopathy (ANE1): management. There is high protein in most cases. There is no pleocytosis. Fully referenced neurology checklist.
Cerebrospinal fluid (CSF) analysis
- There is high protein in most cases
- There is no pleocytosis
- Cell cultures are normal
Magnetic resonance imaging (MRI): features
Locked: subscribe to see this section.
Evoked potentials
Locked: subscribe to see this section.
Treatment
Locked: subscribe to see this section.
Possible outcomes
Locked: subscribe to see this section.
Synonym
Locked: subscribe to see this section.
References
- Denier C, Balu L, Husson B, et al. Familial acute necrotizing encephalopathy due to mutation in the RANBP2 gene. J Neurol Sci 2014 15; 345:236-238.
- Singh RR, Sedani S, Lim M, Wassmer E, Absoud M. RANBP2 mutation and acute necrotizing encephalopathy: 2 cases and a literature review of the expanding clinico-radiological phenotype. Eur J Paediatr Neurol 2015; 19:106-113.
- Di Meglio C, Cano A, Milh M, Girard N, Burglen L, Chabrol B. Postinfectious family case of acute necrotizing encephalopathy caused by RANBP2 gene mutation. Arch Pediatr 2014; 21:73-77.
- Wolf K, Schmitt-Mechelke T, Kollias S, Curt A. Acute necrotizing encephalopathy (ANE1): rare autosomal-dominant disorder presenting as acute transverse myelitis. J Neurol 2013; 260:1545-1553.
- Nishimura N, Higuchi Y, Kimura N, et al. Familial acute necrotizing encephalopathy without RANBP2 mutation: Poor outcome. Pediatr Int 2016; 58:1215-1218.
- And 2 more. Subscribe to see the full list
